Les oméga 3 protègent le coeur

[Nutrimuscle-Conseils]

Fish consumption, omega-3 fatty acids and risk of heart failure: A meta-analysis
Clinical Nutrition Volume 31, Issue 6, December 2012, Pages 846–853 Luc Djousséa,

While marine omega-3 fatty acids have been associated with a lower mortality in heart failure patients, data on omega-3 and incident heart failure are inconsistent. We systematically reviewed the evidence on the association of omega-3 fatty acids and fish intake with the incidence of heart failure in this meta-analysis.

Methods

We identified relevant studies by searching MEDLINE and EMBASE databases up to August 31, 2011 without restrictions and by reviewing reference lists from retrieved articles.

Results

A total of 176,441 subjects and 5480 incident cases of heart failure from 7 prospective studies were included in this analysis. Using random effect model, the pooled relative risk for heart failure comparing the highest to lowest category of fish intake was 0.85 (95% CI; 0.73–0.99), p = 0.04; corresponding value for marine omega-3 fatty acids was 0.86 (0.74–1.00), p = 0.05. There was no evidence for heterogeneity across studies of fish consumption (I2 = 8%). In contrast, there was modest heterogeneity for omega-3 fatty acid analysis (I2 = 44%). Lastly, there was no evidence for publication bias.

Conclusions

This meta-analysis is consistent with a lower risk of heart failure with intake of marine omega-3 fatty acids. These observational findings should be confirmed in a large randomized trial.

[Nutrimuscle-Conseils]

Intake of Fish and Marine n-3 Polyunsaturated Fatty Acids and Risk of Cardiovascular Disease Mortality: A Meta-Analysis of Prospective Cohort Studies
by Lan Jiang Nutrients 2021, 13(7), 2342; h

Previous epidemiological studies have investigated the association of fish and marine n-3 polyunsaturated fatty acids (n-3 PUFA) consumption with cardiovascular disease (CVD) mortality risk. However, the results were inconsistent. The purpose of this meta-analysis is to quantitatively evaluate the association between marine n-3 PUFA, fish and CVD mortality risk with prospective cohort studies. A systematic search was performed on PubMed, Web of Science, Embase and MEDLINE databases from the establishment of the database to May 2021. A total of 25 cohort studies were included with 2,027,512 participants and 103,734 CVD deaths. The results indicated that the fish consumption was inversely associated with the CVD mortality risk [relevant risk (RR) = 0.91; 95% confidence intervals (CI) 0.85−0.98]. The higher marine n-3 PUFA intake was associated with the reduced risk of CVD mortality (RR = 0.87; 95% CI: 0.85–0.89).

Dose-response analysis suggested that the risk of CVD mortality was decreased by 4% with an increase of 20 g of fish intake (RR = 0.96; 95% CI: 0.94–0.99) or 80 milligrams of marine n-3 PUFA intake (RR = 0.96; 95% CI: 0.94–0.98) per day.

The current work provides evidence that the intake of fish and marine n-3 PUFA are inversely associated with the risk of CVD mortality

[Nutrimuscle-Diététique]

Traduction de l'étude

Consommation de poissons et d'acides gras polyinsaturés n-3 marins et risque de mortalité due aux maladies cardiovasculaires : une méta-analyse d'études de cohorte prospectives
par Lan Jiang Nutrients 2021, 13 (7), 2342 ; h

Des études épidémiologiques antérieures ont étudié l'association de la consommation de poisson et d'acides gras polyinsaturés n-3 (AGPI n-3) avec le risque de mortalité par maladie cardiovasculaire (MCV). Cependant, les résultats étaient incohérents. Le but de cette méta-analyse est d'évaluer quantitativement l'association entre les AGPI n-3 marins, les poissons et le risque de mortalité par MCV avec des études de cohorte prospectives. Une recherche systématique a été effectuée dans les bases de données PubMed, Web of Science, Embase et MEDLINE depuis la création de la base de données jusqu'en mai 2021. Au total, 25 études de cohorte ont été incluses avec 2 027 512 participants et 103 734 décès par maladie cardiovasculaire. Les résultats ont indiqué que la consommation de poisson était inversement associée au risque de mortalité par MCV [risque pertinent (RR) = 0,91 ; Intervalles de confiance (IC) à 95 % 0,85-0,98]. L'apport plus élevé d'AGPI n-3 marins était associé à un risque réduit de mortalité par MCV (RR = 0,87 ; IC à 95 % : 0,85 à 0,89).

L'analyse dose-réponse a suggéré que le risque de mortalité par MCV diminuait de 4 % avec une augmentation de 20 g de l'apport en poisson (RR = 0,96 ; IC à 95 % : 0,94-0,99) ou de 80 milligrammes d'apport en AGPI n-3 marins (RR = 0,96 ; IC à 95 % : 0,94 à 0,98) par jour.

Les travaux actuels fournissent des preuves que l'ingestion de poissons et d'AGPI n-3 marins est inversement associée au risque de mortalité par MCV.