Si ça marche en crème, la prise orale doit aider ou on peut la diluer dans de l'eau, mettre un peu de crème hydratante et appliquer le tout
A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne
Angelova-Fischer I J Eur Acad Dermatol Venereol, 2013 July; 27 Suppl 2: 6-11.
In a randomized, double-blind, vehicle-controlled, 9-week study involving 60 subjects (14-40 years of age, 40 women, 20 men, mean age: 22.4 years) with mild to moderately severe acne (10-25 inflammatory lesions) involving the face, application of a topical skin formulation containing licochalcone A, l-carnitine and 1,2-decanediol, twice a day for a period of 8 weeks, was found to be associated with a significant reduction in the pustules and sebum levels, marked reduction in P. acnes and improvement in DLQI, while no such changes were found in the group who applied a placebo vehicle. By the end of the study period, those who used the active product were found to have significant reductions in total lesion count, papules and pustules, P. acnes colonization, sebum production and more pronounced improvement of life quality. The authors conclude, "Our results provide evidence for improved outcomes in result of the application of the active formulation compared to the vehicle from both physician's and patient's perspective."