L'élimination du phosphate diminue avec l'age ce qui augmente les risques de calcification et donc les besoins en vitamines K
Phosphate excretion is decreased in older cardiac patients with normal kidney function: an emerging dietary risk factor?
Alexis Jozefack Applied Physiology, Nutrition, and Metabolism 2016
Serum phosphate independently predicts cardiovascular events and mortality. Sixteen healthy adults and 9 adults with cardiovascular disease (CVD) ingested 500 mg of sodium phosphate after an over-night fast. In control subjects, the urine phosphate/creatinine ratio was significantly higher at 2 h (3.12 ± 1.02) than at baseline (1.98 ± 0.58, p < 0.001) but no change was observed in CVD patients. Decreased postprandial urinary excretion of phosphate could accelerate vascular calcification and may be an under-recognized risk factor for CVD.