Hydrolysat d'élastine ?

[audiomaniac]

Que pensez vous de ce supplément pour les articulations ?

[audiomaniac]

Les tissus riches en élastine sont l’aorte (de 30% à 57%), les vaisseaux sanguins (de 28% à 32%), des ligaments (50%), les poumons (de 3% à 7%), les tendons (4%) et la peau (de 2% à 3%)

Je ne pensais pas autant pour les ligaments !

[audiomaniac]

You've heard about this ingredient in your skin--but do you know it's also a critical component of your vital organs? Research in elastin preservation and regeneration may be the key to future longevity.

[audiomaniac]

These results demonstrate that elastin provides significant resistance to elongation transverse to the collagen axis and shear along the collagen axis while only constituting 4% of the tissue dry weight. The magnitudes of the elastin contribution to peak transverse and shear stress were approximately 0.03 MPa, as compared to 2 MPa for axial tensile tests, suggesting that elastin provides a highly anisotropic contribution to the mechanical response of ligament and is the dominant structural protein resisting transverse and shear deformation of the tissue.

https://www.sciencedirect.com/science/a ... 6115300131

[audiomaniac]

Development of Tissue‐Engineered Ligaments: Elastin Promotes Regeneration of the Rabbit Medial Collateral Ligament

https://onlinelibrary.wiley.com/doi/abs ... /aor.13066

[audiomaniac]

Elastin treatment increased gene expression and protein content of collagen and elastin (gene expression, 6‐fold and 42‐fold, respectively; protein content, 1.6‐fold and 1.9‐fold, respectively), and also increased the elastic modulus of MCL increased with elastin treatment (2‐fold) compared with the controls. Our data suggest that elastin is involved in the regeneration of damaged ligaments

[audiomaniac]

Je ne comprends pas tout mais ça à l'air d'innover dans la régénération des tissus mous

https://www.frontiersin.org/articles/10 ... 00052/full

[audiomaniac]

On va te faire une prise de sang avant de t'embaucher :

Ligament injury rate, severity and recovery time are related to specific genotypes observed in the elastin gene, especially the ELN-AA (16 MCL) and the ELN-AG (3 MCL). Players with the ELN-GG genotype sustained no MCL injury during the 7 seasons of the study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115249/

[audiomaniac]

Un peu de Crispr-cas9 et on pourrait faire de toi un invincible.

Est ce la raison pour laquelle les gens qui ont moins de rides "génétiquement" seraient enclin à être moins facilement blessé ? je pense aux noirs par exemple ?

[audiomaniac]

Alors que l'on sait depuis longtemps que les fibres élastiques jouent un rôle important dans la mécanique des tissus riches en élastine (vasculature, peau, poumons), des études récentes ont suggéré un rôle mécanique des fibres élastiques dans les tendons dépendant de leur fonction spécifique

https://asmedigitalcollection.asme.org/ ... om-Elastin

[audiomaniac]

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing

https://www.nature.com/articles/s41598-017-09995-4

[audiomaniac]

L'hydrolysat d'élastine dérivé du poisson augmente la prolifération des fibroblastes de la peau humaine et la synthèse de l'élastine dans les fibroblastes de la peau humaine et améliore les conditions de la peau

https://onlinelibrary.wiley.com/doi/abs ... /jsfa.7270

[audiomaniac]

A Finalized Protocol for Testing Bovine Tendon to Study the Mechanical Effects of Elastin

https://openscholarship.wustl.edu/cgi/v ... xt=mems500

[audiomaniac]

Overall, the completion and validation of methods for the semester means that our group
can finally start to understand the relationship between the mechanical properties of tendon and
elastin. These results are exciting and important, as we can apply what we learn from these larger
tendons to a human model. This allows us to know more about diseases such as Marfan
Syndrome, which is caused by a mutation in elastic fiber-related genes. Therefore we can learn if
the problems associated with Marfan Syndrome are due to the change of mechanical properties
in tendon because of the deficiency of elastin. In conclusion, this semester’s work has gotten us
closer to discovering more about the relationship between elastin and tendon mechanics.

[audiomaniac]

Cela pourrait être par exemple la cause de cardiopathie congénitale apparement