Potential Role of Branched-Chain Amino Acid Catabolism in Regulating Fat Oxidation
Exercise & Sport Sciences Reviews: October 2013 - Volume 41 - Issue 4 - p 194–200 Kainulainen, Heikki
Insulin-resistant or obese individuals have increased serum branched-chain amino acid (BCAA) levels. Recent findings relate increased BCAA catabolism to increased fatty acid oxidation and better metabolic health in physically active individuals. We hypothesize that, via glyceroneogenesis, BCAA catabolism mediates increased constitutive use of fatty acids for β-oxidation in subjects with increased inherent or acquired aerobic capacity both during exercise and at rest.