The increased amount of coffee consumption lowers the incidence of fatty liver disease in Korean men
Hye-Kyung Chung Nutrition, Metabolism and Cardiovascular Diseases - June 3, 2020
Highlights
•Coffee is known to have a beneficial effect on various liver diseases.
•Coffee consumption at baseline was not associated with the incident fatty liver disease.
•Increasing the amount of coffee consumption lowers the incident fatty liver disease.
Background and aims
Coffee is known to have a beneficial effect on various liver diseases. The aim of this retrospective longitudinal study was to investigate an association between the amount of coffee consumption and the incidence of fatty liver disease in Korean adults.
Methods and results
Data from total 91,436 male and female subjects with the mean follow-up period of 2.8 years were analyzed. The incidence of fatty liver was not associated with the amount of coffee consumption at baseline, but it was associated with the change in the amount of coffee consumption at the follow-up period. Multiple linear regression analyses showed that HRs for incidence of fatty liver disease were significantly low in “increase” group comparing to “no change” group in fully adjusted model. When subgroup analysis by gender was conducted, similar significant results were observed in male subjects, but not in females.
Conclusions
The increment in the amount of coffee consumption is associated with the lower incidence of fatty liver in Korean men and suggests that increasing the coffee consumption may have a protective effect on fatty liver.