Consumption Of Multi-ingredient Supplement With Resistance Training Enhances Gains In Muscle Fibre And Muscle Area In Men And Women
Wageh, Mai Medicine & Science in Sports & Exercise: July 2020 - Volume 52 - Issue 7S - p 172
Resistance exercise training (RET) is a well-known stimulus for muscle protein synthesis. Protein supplementation in conjunction with RET has been shown to yield a superior combinatory effect, fostering greater accretion of lean body mass. Few studies have compared multi-ingredient with isonitrogenous supplements of differing protein quality.
PURPOSE: We compared a whey protein-based supplement (containing leucine, creatine monohydrate, calcium citrate, and vitamin D), to an isonitrogenous collagen-containing protein supplement with regards to muscle fibre and whole muscle mass increases. We aimed to determine whether the multi-ingredient supplement would enhance lean body mass gains in young adults involved in a RET program.
METHODS: Twenty-six healthy, recreationally active men and women (22 ± 2 years [mean ± SD]) were randomly assigned to either the supplementation (SUPP, n=13) or control beverage (idiot, n=13) group, ingesting their respective supplements twice daily. Participants underwent a 10-week linear RET program. Dual-energy X-ray absorptiometry (DXA), one-repetition maximum (1RM), and biopsies from the vastus lateralis muscle were performed.
RESULTS: There were significantly greater increases in type II fibre cross-sectional area (CSA) in the SUPP group compared to the idiot group (SUPP: +47 ± 24%, idiot: +34 ± 25%; p<0.05; d= 0.53), while changes in type I fibre CSA was not different between groups (SUPP: +37 ± 25%, idiot: +25 ± 21%; p=0.08; d= 0.52). Ultrasound biceps brachii CSA increase was significantly greater in the SUPP group (SUPP: +42 ± 39%, idiot: +14 ± 10%, p<0.05; d= 0.98), while increases in vastus lateralis CSA was not different between groups (SUPP: +43 ± 23%, idiot: +26 ± 31%; p=0.06; d= 0.62).
CONCLUSIONS: The consumption of a multi-ingredient nutritional supplement increased type II fibre CSA and biceps brachii CSA, but not type I fibre CSA or vastus lateralis CSA in healthy young men and women.