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Supprimer les sucres pour supprimer un cancer?

Messagepar Nutrimuscle-Conseils » 25 Jan 2020 20:09

In vitro quantification: long-term effect of glucose deprivation on various cancer cell lines
Edward Henry Mathews Nutrition Available online 25 January 2020,


Highlights
• Long-term (90 days) in vitro glucose deprivation was done on various cancer cell lines.
• Most effected cell line: Tumorigenic MDA-MB-231 minimum cell growth of 30% on day 26.
• Least effected cell line: Non-tumorigenic MCF-10A remaining stable at 84% on day 34.

• Long-term glucose deprivation affects different
• time for implementing adjuvant therapies was determined to be 26 days.


ABSTRACT
Objective
Although metabolic treatment of highly glycolytic cancers and metastases is becoming an important research field, the effects of such treatments are not fully quantified yet. In this article we attempt to quantify the effect of long-term glucose deprivation (similar to Ketogenic Diets etc.) on cancer cells using in vitro tests.

Research methods and procedures
Two tumorigenic cell lines were used, namely a metastatic breast and a cervical cancer cell line. The non-tumorigenic control cell line was an immortalized breast cell line. All the cell lines were stabilized at a typical average human blood glucose (BG) level of 6mmol/L. The cell lines were then exposed to the therapeutic BG level of 3mmol/L for 90 days.

Results
The tests showed that glucose deprivation restricted the different cancer cell lines’ growth more than that of non-tumorigenic cells. The different cell lines were also differentially affected, which suggests that long-term glucose deprivation will not be equally effective for different types of cancer.

The highly glycolytic breast cancer cell line was most adversely affected, with cell growth decreasing to 30% after 26 days. Cell growth was stable at this level for up to 22 days. Furthermore, all of the other cancer cell lines were similarly affected. This in vitro data could help to direct future human in vivo tests to find the most therapeutic time (cancer cells at their most vulnerable) for additional short-term adjuvant therapies.

Partial recovery of proliferation occurred after 90 days. Therefore, as expected, the results also show that without an adjuvant treatment, full extinction cannot be reached with the proposed long-term metabolic treatment.

Conclusion
The need for more clinical data on long-term glucose deprivation treatments for cancer is well described in literature. This paper attempts to add to the available pool of knowledge.
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Re: Supprimer les sucres pour supprimer un cancer?

Messagepar thanos999 » 25 Jan 2020 20:33

ca avait bien fait rigoler le "specialiste" qui s'occupait de mon pere
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