chez les post-adolescents quand l'acné perdure
Insulin Resistance and Metabolic Syndrome in Young Men With Acne
Mohit Nagpal JAMA Dermatol. Published online December 23, 2015.
Introduction Robust evidence of the association of insulin resistance and metabolic syndrome with acne in male patients is lacking.
Objective To assess the prevalence of metabolic syndrome and insulin resistance in male patients 20 years or older with acne.
Results Prevalence of insulin resistance was significantly higher in cases (22%) compared with controls (11%) (P = .03). The prevalence of metabolic syndrome was comparable between cases (17%) and controls (9%) (P = .09). Prevalence of insulin resistance and metabolic syndrome did not differ significantly among the acne severity groups.
Conclusions and Relevance Postadolescent male patients with acne more commonly have insulin resistance. This resistance may be a stage of prediabetes, and the patients may develop hyperinsulinemia or type 2 diabetes in the future. These patients should be followed up for a prolonged time to determine whether they develop conditions associated with insulin resistance.