Influence alimentaires sur le risque de calculs rénaux?

[Nutrimuscle-Conseils]

Association of dietary live microbe intake with kidney stone disease in US adults: a real-world cross-sectional study
Zhongyi Zheng Front. Nutr., 21 October 2024

Background: Kidney stone disease (KSD) is a common urological condition linked with hypertension, chronic kidney disease, and other health issues. Although the gut microbiome has a notable association with KSD formation, the relationship between dietary live microbes and KSD risk remains underexplored.

Methods: This study utilized data from the NHANES surveys conducted between 2007 and 2016 to analyze the association between dietary live microbe intake and KSD. Dietary intake data were obtained through 24-h dietary recall interviews conducted by trained professionals. Participants were categorized into three groups based on Sanders’ classification system of dietary live microbe intake: low, medium, and high. The intake levels were determined by estimating the live microbe content in foods. Weighted logistic regression analysis was employed to account for the complex survey design and to assess the impact of different levels of live microbe intake on KSD risk.

Results: A total of 20,380 participants were included in the study. Participants with low, medium, and high dietary microbe intake represented 33, 39, and 28% of the cohort, respectively. The adjusted odds ratios (ORs) for KSD were 0.78 (95% CI, 0.65–0.93) in the high dietary live microbe group compared to the low group (p < 0.05). Subgroup analyses revealed no significant interactions between dietary live microbe intake and gender, age, BMI, hypertension, or diabetes status.

Conclusion: Higher dietary live microbe intake group may be associated with a reduced risk of KSD. Further prospective studies are necessary to validate these findings and to elucidate the specific mechanisms and optimal intake levels of dietary microbes.

[Nutrimuscle-Diététique]

Traduction de l'étude

Association entre l'apport alimentaire de microbes vivants et la maladie des calculs rénaux chez les adultes américains : une étude transversale en situation réelle
Zhongyi Zheng Front. Nutr., 21 octobre 2024

Contexte : La maladie des calculs rénaux (MCR) est une affection urologique courante liée à l'hypertension, à la maladie rénale chronique et à d'autres problèmes de santé. Bien que le microbiome intestinal ait une association notable avec la formation de MCR, la relation entre les microbes vivants alimentaires et le risque de MCR reste sous-explorée.

Méthodes : Cette étude a utilisé les données des enquêtes NHANES menées entre 2007 et 2016 pour analyser l'association entre l'apport alimentaire de microbes vivants et la MCR. Les données sur l'apport alimentaire ont été obtenues au moyen d'entretiens de rappel alimentaire de 24 heures menés par des professionnels qualifiés. Les participants ont été classés en trois groupes en fonction du système de classification de Sanders de l'apport alimentaire de microbes vivants : faible, moyen et élevé. Les niveaux d'apport ont été déterminés en estimant la teneur en microbes vivants des aliments. Une analyse de régression logistique pondérée a été utilisée pour tenir compte de la conception complexe de l'enquête et pour évaluer l'impact de différents niveaux d'apport en microbes vivants sur le risque de KSD.

Résultats : Au total, 20 380 participants ont été inclus dans l'étude. Les participants ayant un apport alimentaire en microbes faible, moyen et élevé représentaient respectivement 33, 39 et 28 % de la cohorte. Les rapports de cotes ajustés (RC) pour le KSD étaient de 0,78 (IC à 95 %, 0,65-0,93) dans le groupe ayant un apport alimentaire élevé en microbes vivants par rapport au groupe ayant un apport faible (p < 0,05). Les analyses de sous-groupes n'ont révélé aucune interaction significative entre l'apport alimentaire en microbes vivants et le sexe, l'âge, l'IMC, l'hypertension ou le statut diabétique.

Conclusion : Le groupe ayant un apport alimentaire plus élevé en microbes vivants peut être associé à un risque réduit de KSD. D'autres études prospectives sont nécessaires pour valider ces résultats et pour élucider les mécanismes spécifiques et les niveaux d'apport optimaux en microbes alimentaires.

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The potential role of alkaline diets in prevention of calcium oxalate kidney stone formation
Food & Function Issue 24, 2024 Doha A. Mohamed

Formation of kidney stones is considered a major global problem. Diet plays an important role in the management of kidney stone formation. The main goal of the present research was to evaluate the protective role of fruit and vegetable mixtures as models of an alkaline diet on formation of kidney stones in rats and to conduct molecular docking study. The chemical compositions, phenolic compound profile, β-carotene content, vitamin C and antioxidant activity of both mixtures were assessed. Fruit (−42.419 ) and vegetable (−11.13) mixtures recorded a negative potential renal acid load in the presence of macro-/micro-nutrients, β-carotene and phenolic compounds; chlorogenic acid was the major content in both mixtures. Both mixtures exhibited high antioxidant activity. Molecular docking study proved that rutin displayed the highest binding affinities for glycolate oxidase (−11.8 kcal mol−1) and lactate dehydrogenase (−10.1 kcal mol−1).

The kidney stone model in rats exhibited metabolic acidosis in the urinary profile through reduction of citrate; Ca, Mg and K excretion and elevation of oxalate, creatinine, creatinine clearance, uric acid, urea and protein. Additionally, there was a significant reduction in plasma Ca, Mg and K levels, while liver and kidney function parameters improved significantly. Fruit and vegetable mixtures as models of an alkaline diet proved improvement in all the parameters. Histopathological examination of kidney sections of the kidney stone model showed crystal deposition, inflammation, and severe necrosis.

Kidney sections of alkaline diet models indicated mild and moderate changes. Conclusion: The results of this study proved that both alkaline diet models were effective in protecting against kidney stone formation in vivo and in molecular docking studies.

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Habitual tea consumption is associated with a lower prevalence of kidney stone disease in postmenopausal women
Kuan-Hsien Wu Peer J 2024

Background
Menopause is associated with an increased risk of kidney stone disease (KSD). However, for postmenopausal women, how to avoid KSD has rarely been studied. The aim of this study was to explore whether drinking tea is associated with a reduction in the prevalence of KSD in postmenopausal women.

Methods
We collected 11,484 postmenopausal women from the Taiwan Biobank, and used questionnaires to obtain information on tea drinking, KSD, and comorbidities. The participants were divided into two groups according to habitual tea consumption: tea-drinking and non-tea-drinking groups. The association between habitual tea consumption and KSD was examined by logistic regression analysis.

Results
There were 2,035 postmenopausal women in the tea-drinking group and 9,449 postmenopausal women in the non-tea-drinking group. The mean age of all participants was 61 years. Compared to the non-tea-drinking group, the tea-drinking group had a significantly lower prevalence of KSD (7% vs. 5%). The odds ratio (OR) of KSD was lower in those who habitually drank tea than in those who did not (OR = 0.78; 95% confidence interval [CI] [0.63 to 0.96]) after adjusting for confounders. Moreover, postmenopausal women with a daily intake of two cups of tea or more had a 30% reduced risk of KSD compared to those who did not habitually drink tea (OR = 0.71, 95% CI [0.56 to 0.90]).

Conclusions
Our results suggest that habitual tea drinking may be associated with a reduction in the prevalence of KSD in postmenopausal women. Further studies are warranted to investigate the protective effect of tea on the development of KSD.

[Nutrimuscle-Diététique]

Traduction de l'étude

La consommation habituelle de thé est associée à une prévalence plus faible de calculs rénaux chez les femmes ménopausées
Kuan-Hsien Wu Peer J 2024

Contexte
La ménopause est associée à un risque accru de calculs rénaux. Cependant, chez les femmes ménopausées, les moyens d'éviter les calculs rénaux ont rarement été étudiés. L'objectif de cette étude était de déterminer si la consommation de thé est associée à une réduction de la prévalence des calculs rénaux chez les femmes ménopausées.

Méthodes
Nous avons recueilli 11 484 femmes ménopausées de la Taiwan Biobank et utilisé des questionnaires pour obtenir des informations sur la consommation de thé, les calculs rénaux et les comorbidités. Les participantes ont été divisées en deux groupes en fonction de leur consommation habituelle de thé : les groupes buveurs de thé et les groupes non buveurs de thé. L'association entre la consommation habituelle de thé et les calculs rénaux a été examinée par analyse de régression logistique.

Résultats
Le groupe buveur de thé comprenait 2 035 femmes ménopausées et le groupe non buveur de thé comprenait 9 449 femmes ménopausées. L'âge moyen de toutes les participantes était de 61 ans. Par rapport au groupe non buveur de thé, le groupe buveur de thé présentait une prévalence de KSD significativement plus faible (7 % contre 5 %). Le rapport de cotes (RC) de KSD était plus faible chez les femmes qui buvaient habituellement du thé que chez celles qui n'en buvaient pas (RC = 0,78 ; intervalle de confiance [IC] à 95 % [0,63 à 0,96]) après ajustement pour les facteurs de confusion. De plus, les femmes ménopausées qui consommaient quotidiennement deux tasses de thé ou plus présentaient un risque réduit de 30 % de KSD par rapport à celles qui ne buvaient pas habituellement de thé (RC = 0,71, IC à 95 % [0,56 à 0,90]).

Conclusions
Nos résultats suggèrent que la consommation habituelle de thé peut être associée à une réduction de la prévalence du syndrome de König-Schmidt chez les femmes ménopausées. D'autres études sont nécessaires pour étudier l'effet protecteur du thé sur le développement du syndrome de König-Schmidt.

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Self-Reported Symptoms of Obstructive Sleep Apnea are Associated with Increased Risk of Kidney Stones: A Cross-Sectional Study from NHANES 2015-2020
Du D Nature and Science of Sleep 2024 Volume 2024:16 Pages 2099—2110

Objective: To investigate whether self-reported symptoms of obstructive sleep apnea (OSA), including snoring, snorting/stopping breathing, and sleepiness, are associated with increased risk of kidney stones.
Methods: This cross-sectional study was conducted based on the 2015– 2020 National Health and Nutrition Examination Survey (NHANES). Self-reported symptoms of OSA and history of kidney stones were diagnosed via questionnaires. Multivariable logistic regression was used to determine the associations between self-reported symptoms of OSA and kidney stones. Subgroup analyses and interaction tests were performed to address this issue further.
Results: A total of 9,973 participants were enrolled, and the prevalence of kidney stones was 10.76%. Although no significant association was observed between frequent snoring and kidney stones after covariate adjustments (OR 1.033, 95% CI 0.726, 1.469 p = 0.850), frequent snorting/stopping breathing was associated with a greater risk of kidney stones after covariate adjustments (OR 1.655, 95% CI 1.262, 2.172, p = 0.002). Participants who often or almost always felt sleepy also had a greater risk of kidney stones after covariate adjustment (OR 1.651, 95% CI 1.222, 2.229; p = 0.004). The interaction tests suggested that marital status (p = 0.015) and smoking status (p < 0.001) significantly interacted with the association between snorting/stopping breathing and kidney stones.
Conclusion: Self-reported frequent snorting/stopping breathing and sleepiness may be associated with increased risk of kidney stones. Although these findings may emphasize prevention of kidney stones in these people, further research was still needed to verify our results.