Vitamine D3

[Persephone]

Vitamin D Deficiency: An Important, Common, and Easily Treatable Cardiovascular Risk Factor?

Vitamin D deficiency is a highly prevalent condition, present in approximately 30% to 50% of the general population. A growing body of data suggests that low 25-hydroxyvitamin D levels may adversely affect cardiovascular health. Vitamin D deficiency activates the renin-angiotensin-aldosterone system and can predispose to hypertension and left ventricular hypertrophy. Additionally, vitamin D deficiency causes an increase in parathyroid hormone, which increases insulin resistance and is associated with diabetes, hypertension, inflammation, and increased cardiovascular risk. Epidemiologic studies have associated low 25-hydroxyvitamin D levels with coronary risk factors and adverse cardiovascular outcomes. Vitamin D supplementation is simple, safe, and inexpensive.

http://content.onlinejacc.org/cgi/conte ... 52/24/1949

[Persephone]

Interview exclusive de Rheinhold Vieth sur LaNutrition

[Bodyfab]

dommage c'est réservé aux abonnés...

[dave75]

Je m'interresse beaucoup à la vitamine D (D3) en ce moment (merci Persephone)...

J'en ai parlé à un doc qui m'a rétorqué que si l'on prenait suffisamment le soleil en été, l'on avait "sa dose" de D pour le restant de l'année et que -donc- la prise de D3 en supplément était inutile.

Que répondre à cela ?

[Nutrimuscle-Conseils]

si l'on prenait suffisamment le soleil en été, l'on avait "sa dose" de D pour le restant de l'année

si c'est le cas, je pense qu'un dermato te dirait que tu restes trop au soleil

[dave75]

Bon, de toute manière, avant même ma prise de sang, j'ai commandé de la D3 dosé à 1000 ui la gélule. J'en ai pris une aujourd'hui... On verra ce que ça donne...

[Persephone]

Que la demi-vie de la vitamine D3 est d'environ 1 mois, donc que ce que l'on ne peut pas en avoir suffisamment en allant simplement en hiver.

Mais le plus simple pour couper court à toute polémique est de faire une prise de sang.


1000IU par jour, comme tu as pu le lire, c'est presque rien.

[Persephone]

Vitamin D Status and its Relationship to Body Fat, Final Height, and Peak Bone Mass in Young Women.

Unexpectedly, there was a positive correlation between 25OHD levels and height.

http://www.ncbi.nlm.nih.gov/pubmed/18984659

[Persephone]

Vitamin D status of females in an elite gymnastics program.

Eighteen female gymnasts aged 10-17 years were assessed for vitamin D status (serum 25[OH]D) and dietary calcium intake

Fifteen were found to have levels below current recommended guidelines for optimal bone health (<75 nmol/L). Six had vitamin D levels below 50 nmol/L. Thirteen of the gymnasts also had daily dietary calcium intakes below the daily recommended intake for their age.

Gymnasts and possibly other indoor athletes should be carefully reviewed for vitamin D and calcium status.

http://www.ncbi.nlm.nih.gov/pubmed/18332692

[thanos999]

en pharmacie ca coute combien?

[Persephone]

Comme tu vas certainement faire, très consciencieusement , une prise de sang, tu pourras avoir une ordonnance et ce sera remboursé.

Sinon, sans ordonnance, en pharmacie il n'y a que ZYMAD en flacon compte-gouttes de 10mL (10 000IU/mL) et qui coûte 2.73€.

[thanos999]

ok merci

[Nutrimuscle-Conseils]

le niveau de vitamine D dans le sang baisse encore (aux US au moins)

Serum 25-hydroxyvitamin D status of the US population: 1988–1994 compared with 2000–2004

American Journal of Clinical Nutrition, Vol. 88, No. 6, 1519-1527, December 2008


Background: Changes in serum 25-hydroxyvitamin D [25(OH)D] concentrations in the US population have not been described.

Objective: We used data from the National Health and Nutrition Examination Surveys (NHANES) to compare serum 25(OH)D concentrations in the US population in 2000–2004 with those in 1988–1994 and to identify contributing factors.

Design: Serum 25(OH)D was measured with a radioimmunoassay kit in 20 289 participants in NHANES 2000–2004 and in 18 158 participants in NHANES III (1988–1994). Body mass index (BMI) was calculated from measured height and weight. Milk intake and sun protection were assessed by questionnaire. Assay differences were assessed by re-analyzing 150 stored serum specimens from NHANES III with the current assay.

Results: Age-adjusted mean serum 25(OH)D concentrations were 5–20 nmol/L lower in NHANES 2000–2004 than in NHANES III. After adjustment for assay shifts, age-adjusted means in NHANES 2000–2004 remained significantly lower (by 5–9 nmol/L) in most males, but not in most females. In a study subsample, adjustment for the confounding effects of assay differences changed mean serum 25(OH)D concentrations by 10 nmol/L, and adjustment for changes in the factors likely related to real changes in vitamin D status (ie, BMI, milk intake, and sun protection) changed mean serum 25(OH)D concentrations by 1–1.6 nmol/L.

Conclusions: Overall, mean serum 25(OH)D was lower in 2000–2004 than 1988–1994. Assay changes unrelated to changes in vitamin D status accounted for much of the difference in most population groups. In an adult subgroup, combined changes in BMI, milk intake, and sun protection appeared to contribute to a real decline in vitamin D status.

[Nutrimuscle-Conseils]

si vous ne voulez pas faire de prise de sang, voilà les dosages de vitamine D moyens à prendre : de 28 µg (1 280 UI) à 41 µg ( 1640 UI) par jour pour ceux qui ne vont pas au soleil

Estimation of the dietary requirement for vitamin D in healthy adults

Background: Knowledge gaps have contributed to considerable variation among international dietary recommendations for vitamin D.

Objective: We aimed to establish the distribution of dietary vitamin D required to maintain serum 25-hydroxyvitamin D [25(OH)D] concentrations above several proposed cutoffs (ie, 25, 37.5, 50, and 80 nmol/L) during wintertime after adjustment for the effect of summer sunshine exposure and diet.

Design: A randomized, placebo-controlled, double-blind 22-wk intervention study was conducted in men and women aged 20–40 y (n = 238) by using different supplemental doses (0, 5, 10, and 15 µg/d) of vitamin D3 throughout the winter. Serum 25(OH)D concentrations were measured by using enzyme-linked immunoassay at baseline (October 2006) and endpoint (March 2007).

Results: There were clear dose-related increments (P < 0.0001) in serum 25(OH)D with increasing supplemental vitamin D3. The slope of the relation between vitamin D intake and serum 25(OH)D was 1.96 nmol·L–1·µg–1 intake. The vitamin D intake that maintained serum 25(OH)D concentrations of >25 nmol/L in 97.5% of the sample was 8.7 µg/d. This intake ranged from 7.2 µg/d in those who enjoyed sunshine exposure, 8.8 µg/d in those who sometimes had sun exposure, and 12.3 µg/d in those who avoided sunshine. Vitamin D intakes required to maintain serum 25(OH)D concentrations of >37.5, >50, and >80 nmol/L in 97.5% of the sample were 19.9, 28.0, and 41.1 µg/d, respectively.

Conclusion: The range of vitamin D intakes required to ensure maintenance of wintertime vitamin D status [as defined by incremental cutoffs of serum 25(OH)D] in the vast majority (>97.5%) of 20–40-y-old adults, considering a variety of sun exposure preferences, is between 7.2 and 41.1 µg/d.

[audiomaniac]

Ca parait faible par rapport a ce que disait Persephone surtout pour des personnes qui ne vont pas au soleil